UH ORGANIC CHEMISTRY
Chapter 11A: Alcohol Reactions
Brief Summary
- Oxidation of Alcohol
- Secondary Alcohols (To Ketone)
- Chromic Acids
- Na2Cr2O7/H2SO4/H2O
- CrO3/H2SO4/H2O/Acetone/0C
- Jones' Reagent
- Others
- KMnO4 OR HNO3 OR NaOCl
- PCC/CH2Cl2
- Chromic Acids
- Primary Alcohol
- To Aldehyde: ONLY PCC/CH2Cl2
- To Carboxylic Acids: Any Chromic Acids
- Secondary Alcohols (To Ketone)
- Alcohol Substitution
- Tosylate ester: TsCl/Pyridine
- Halide substitution
- PBr3 --> R--Br
- PCl3 OR SOCl2 --> R-Cl
- PBr3 --> R--Br
- Special Alkene Synthesis:
- POCL3 -- Dehydration of ANY alcohol molecules
- Ether Synthesis
- 2 yields of alcohol + H2SO4 = ether
- Williamson Ether Synthesis
- Alkoxide + alkyl halide = ether